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Differentiation

Identification of specific epidermal differentiation markers in AST2000

Immunohistochemical labeling of Involucrin, a protein expressed by keratinocytes of the suprabasal and upper layer of the epidermis.

Immunohistochemical labeling of Cytokeratin 5/14, proteins expressed in the basal layers of the epidermis.
Immunohistochemical labeling of Integrin beta 1, a protein expressed by keratinocytes in the basal layer of the epidermis.
Electron microscopy view to the surface of the cornified layer
(flat, broad and cornified keratinocytes).

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