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Worthington

Tissue Dissociation
Collagenase Type IV from Worthington Biochemical Corporation*

Collagenase Type 4 selected because of low tryptic activity. It is commonly used for islets and other applications where receptor integrity is crucial.

Correlations between type and effectiveness with different tissues have been good, but not perfect, due in part to variable parameters of use. Nevertheless most researchers consider the tissue-typing of crude collagenase lots to be a valuable service.

* Text is quoted from the Worthington Enzyme Manual

Product Highlight: Collagenase

Product Name Description Activity Quantity Cat.No.
Collagenase, Type 4

Code CLS-4

 Prepared to contain lower tryptic activity levels to limit damage to membrane proteins and receptors but with normal to above normal collagenase activity. Suggested for pancreatic islet. Source: Clostridium histolyticum. Storage Conditions: Store at
2-8°C.		 ≥160 units per mg dry weight 1 gm

5 gm

Bulk

 LS004188

LS004189

LS004191
Collagenase, Type 4, Filtered

Code CLSS-4

 Collagenase, Type 4 (Code: CLS-4), which is filtered through a 0.22 micron membrane and lyophilized in vials to contain ≥ 50 milligrams per vial. Source: Clostridium histolyticum. Storage Conditions: Store at 2-8°C. ≥160 units per mg dry weight 50 mg

5x50 mg

 LS004210

LS004212

Collagenase Sampling Program:

Under the program, individual researchers are provided with 100 mg samples of up to three different lots of collagenase for evaluation in their own assay systems. A minimum of 3 grams of each lot will be placed on HOLD, reserved in your name. When you determine which lot performs best for you, simply specify the lot desired when ordering. Please contact us for further information.

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